Clinical Usefulness of Combination Therapy with Minocycline and Ciprofloxacin as a Treatment for Fulminant Cases of Japanese Spotted Fever

نویسندگان

  • Fumihiko Mahara
  • Kazuaki Miyamoto
  • Hiromi Fujita
  • Teruo Mutsuda
چکیده

Fumihiko Mahara1,2, Kazuaki Miyamoto1,2*, Hiromi Fujita2 and Teruo Mutsuda1 1Mahara Hospital, Aratono-cho Nobusato 6-1, Anan, 779-1510, Japan 2Mahara Institute of Medical Acarology, Aratano-cho Korekuni 56-3, Anan, 779-1510, Japan *Corresponding author: Kazuaki Miyamoto, Mahara Institute of Medical Acarology, Aratano-cho Korekuni 56-3, Anan, 779-1510, Japan, Fax/Tel: +81-884-36-3601; Email: [email protected]

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Fulminant Japanese spotted fever associated with hypercytokinemia.

We report a patient with Japanese spotted fever caused by Rickettsia japonica who developed shock associated with hypercytokinemia. Elevated levels of cytokines (macrophage colony-stimulating factor, interleukin 1 beta, interleukin 10, and gamma interferon) decreased rapidly after a combination treatment using an antibiotic (minocycline hydrochloride [MINO]) and methylprednisolone; however, tum...

متن کامل

The Effectiveness of Intravenous Levofloxacin Compared to Injectable Ciprofloxacin and Clindamycin in the Treatment of Foot Ulcer Infection in Diabetic Patients Hospitalized in the Infectious Ward of the Hospital

Introduction: Diabetic foot ulcer is one of the most common problems in diabetic patients, hospitalized in infectious ward. Given various side effects of many antibiotics, the precise determination of the type of antibiotic used with the least side effects has great clinical importance. In this regard, the present study was conducted to compare the effectiveness of injectable levofloxacin with ...

متن کامل

Ciprofloxacin therapy for Mediterranean spotted fever.

We report the treatment of five patients with Mediterranean spotted fever with the antimicrobial agent ciprofloxacin. The treatment was administered intravenously for 2 days and then perorally for 8 days. All five patients were cured. These preliminary data seem to correlate with the in vitro activity of ciprofloxacin against Rickettsia conorii.

متن کامل

Severe Japanese spotted fever successfully treated with fluoroquinolone.

A 77 years old woman who had a bite with eschar on her left arm, was admitted to emergency ward in our hospital, because of high fever, severe malaise, skin eruption, and consciousness disturbance beginning 5 days previously. She was diagnosed as Japanese spotted fever by seropositive of Rickettsia japonica (R. japonica) antibody, and successfully treated with fluoroquinolone, after minocycline...

متن کامل

A case of Japanese spotted fever complicated with central nervous system involvement and multiple organ failure.

Japanese spotted fever (JSF), first reported in 1984, is a rickettsial disease characterized by high fever, rash, and eschar formation. A 61-year-old man was admitted to a local hospital in Nagasaki City, Japan, after several days of high fever and generalized skin erythema. His condition deteriorated and laboratory findings indicated disseminated intravascular coagulation (DIC). The patient wa...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014